Antagonistic and Antibacterial Activity of Stapylocossus aureus and Isolates of Oral Bacteria from the Endogenous Fungus Apis dorsata Binghami Nest

Apis Dorsata Binghami honey bee is a endemic to Indonesia, living naturally in the forests of Sulawesi. This study aimed obtain isolates and characteristics endogenous fungi antibiotic activity from dorsata nest. The research consisted isolation beehives using potato dextro agar, pure culture fungi, antagonist test disc diffusion method. Antibiotic was performed on oral bacteria Staphylococcus aureus. results obtained six nest Binghami, namely FAB1, FAB2, FAB3, FAB4, FAB5 FAB6. showed that FAB2 FAB3 had best properties, while FAB6 weakest properties. isolate bacterial growth inhibition zone average for lasts up 3 x 24 hours so bactericidal. From this study, it can be concluded fungus potential source antibacterial bioactives.